12/15/2023 0 Comments Cannabidiol nocturnal epilepsy![]() ![]() The brain, and typically produces non-convulsive seizures that involve someĭegree of sensory (visual, auditory, olfactory or even gustatory)ĭisturbance-although it may also produce tonic-clonic seizures in severe cases. As the name suggests, temporal lobe epilepsy affects the temporal lobe of That patients suffering from temporal lobe epilepsy appeared to have dysfunctional endocannabinoid systems. In 2008, a study published in Nature indicated This school of thought was founded by cannabis researcher and PhD, Ethan Russo and includes other neurological conditions such as Parkinson’s, Multiple Sclerosis and Dravet Syndrome. In fact, there is an entire school of thought that suggests epilepsy is actually caused by a dysfunction of the endocannabinoid system (a condition speculatively known as clinical endocannabinoid deficiency), which could arise due to brain injury, infection or genetic predisposition. Neuroprotective benefits of cannabis for epilepsyĪs research into the endocannabinoid system advances, it is becoming clear that it plays an important role in regulating the duration and frequency of seizures. Types of epilepsy including Dravet syndrome in young children, and has gained ground rapidly as a potential treatment Not been established, but it is proving highly effective in treating various Precise mechanism utilised by CBD when working to control convulsions has still Its effect on the CB1-receptors of the central nervous system, delta-9-THC canĪctually cause convulsions in rare cases, whileĬBD does not appear to have this side-effect due to its independent mechanism CBD exerts its effects via a different means, as it does not agonise the CB1-receptor but instead acts as a weak antagonist. A 2001 study demonstrated that delta-9-THC and the synthetic delta-9-THC analogue WIN 55,212-2 exerted their effect by agonising the CB1-receptors. Since then, various studies have found that CBD does, in fact, possess remarkable anticonvulsant properties in its own right, as well as potentiating the effects of delta-9-THC. It was noted that CBD increased the anticonvulsant effect of delta-9-THC,Īlthough the researchers did not find that CBD was effective in its own right. Study conducted at the University of Sydney in 1974 demonstrated that delta-9-THC given in high doses had an anticonvulsant effect on mice that were administered chemical and electrical shocks as a means to Cannabinoids were tested for their anticonvulsant properties by researchers as early as 1947. The anticonvulsant properties of cannabis have been known to humans for centuries, if not millennia. Anticonvulsant benefits of cannabis for epilepsy Now, old research is resurfacing, especially in the case of epilepsy, opening new avenues of medical cannabis as a valid line of treatment. The recreational aspect of cannabis took over public opinion, and despite knowing that cannabis has some remedial properties, it was prohibited for medical use. However, there are many variations of epilepsy, and while Dravet Syndrome is anĮxample of the most severe, there are also forms of epilepsy that are mild.īecause of prohibition during the 1970s, cannabis fell off the radar as a medicinal substance until recently. It is one of the rarer forms of epilepsy, and patients with Dravet Syndrome is one type of severe childhood-onset epilepsy that can cause neurological impairment. Neurons of the brain if severe and prolonged, seizures can result in damage toīrain tissue, particularly in young children, when the brain is still A period of unconsciousnessĬan occur before the person turns to normality.Īnd non-convulsive epileptic seizures are caused by excessive activity in the Tonic-clonic seizure, which involves a short period of contraction of the limbsįollowed by their extension, and uncontrollable shaking. The entire body to shake or jerk uncontrollably. Cannabis and cannabis-based therapies have been shown to have beneficial effects on several types of epilepsy, through a variety of biological mechanisms.Īll epileptic seizures are convulsive, which means that they areĬharacterised by rapid, involuntary contractions of the muscles that can cause Epilepsy refers to a group of conditions characterised by recurrent seizures, which may be convulsive or non-convulsive. ![]()
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